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Eucerin DermoPurifyer Skin Renewal Treatment 40 ml

Blemish-prone skin

A serum with 10% Hydroxy Complex that unclogs pores, visibly reduces blemishes and helps prevent their re-appearance.

Eucerin DermoPurifyer Skin Renewal Treatment 40 ml

The innovative Eucerin DermoPurifyer Skin Renewal Treatment has been specially formulated to reduce the appearance of pimples, papules and pustules as well as to fade acne marks. 

It is suitable for all mild to moderate forms of acne and has a triple effect:

  • The 10% Hydroxy Complex contains a highly effective combination of peeling agents − Glycolic Acid, Salicylic Acid and Polyhydroxy Acid – which help to resurface skin, unclog pores, reduce bacteria, remove dead skin cells and prevent new blemishes from appearing

The formula also contains Licochalcone A which has been proven to reduce inflammation and help soothe irritation.

Eucerin DermoPurifyer Skin Renewal Treatment starts to visibly improve skin after just one week, revealing clearer and smoother-looking skin over time.

Can be used during pregnancy but should not be used by skin undergoing medical acne treatment.

Clinical studies

* In a Product in Use (PIU) study 40 men and women (aged 12-44) with acne-prone skin used the product once a day (in the evening) for eight weeks. Results were assessed after one, two, four and eight weeks of use. The before and after images show the visible results after eight weeks of use.


In a self-assessment study, 80 women between the ages of 15 and 40 applied Eucerin DermoPurifyer Skin Renewal Treatment every evening for eight weeks. They reported the following results:

  • 95%: Helps to control the oiliness of skin
  • 94%: Prevents new blemishes from appearing
  • 94%: Reduces dark post-acne marks
  • 94%: Has an anti-shine effect
  • 94%: Smooths the skin’s surface
  • 94%: Visibly improves skin’s appearance
  • 93%: Diminishes the visibility of pores
  • 88%: Visibly reduces blemishes
  • 85%: Reduces whiteheads
  • 83%: Reduces blackheads
  • 81%: Reduces inflammatory pimples 

Frequently Asked Questions

If I use the serum daily when can I expect to see an improvement?

If used regularly skin will start looking better after just one week.

Can I use the serum in addition to my normal moisturiser and, if so, which should I use first?

Eucerin DermoPurifyer Skin Renewal Treatment combines very well with anti-ageing skincare. We recommend that you use it, in the evenings, alongside Eucerin Hyaluron-Filler Night Cream.

I have both acne-prone and sensitive skin. Can I use Eucerin DermoPurifyer Skin Renewal Treatment?

In principle, yes. But test the product first to ensure it is well tolerated by your skin. You can do this by using a small amount on a small area of skin and leaving it on overnight. If you experience a slight stinging sensation, don’t worry − that just shows that the product is working.

Should I introduce the serum slowly into my routine to help my skin get used to it?

We use a gentle combination of acids that makes the product suitable for use every evening from day one. As with all products, however, it is a good idea to test the product on a small area of your skin before applying it to your full face.

Can I use this product on holiday in very sunny areas?

If the weather is excessively hot we recommend you stop using the treatment. And always be sure to wear sufficient sun protection. We recommend Eucerin Oil Control Sun Gel-Cream Dry Touch SPF 50+.

Do I need to use sun protection the day after applying this treatment?

We recommend that you use the product in the evening because its peeling effect will make your skin more sensitive to UV rays, and more prone to sunburn. And, even after evening use, it’s important you give your skin adequate protection from the sun the next day. We recommend Eucerin Oil Control Sun Gel-Cream Dry Touch SPF 50+.

Why is the pH of the Eucerin DermoPurifyer Skin Renewal Treatment important?

The product’s pH plays an important role in its effectiveness and skin compatibility. Eucerin DermoPurifyer Skin Renewal Treatment has a pH of between 3.7 and 3.9. This low, mildly acidic pH is perfect for the role of this product as it increases its antibacterial effect and its ability to remove dead skin cells.

Can I use the serum in addition to my normal moisturiser and, if so, which should I use first?

Eucerin DermoPurifyer Skin Renewal Treatment can be used alongside other care products such as moisturisers and anti-ageing treatments. We recommend that you use the Skin Renewal Treatment first and in the evening. If you use the Skin Renewal Treatment in the morning be sure to follow with a sunscreen such as Eucerin Oil Control  Sun Gel-Cream Dry Touch SPF 50+.


  • Use once a day. Preferably in the evening.
  • Apply a small amount (about the size of a pea) to a thoroughly cleansed face
  • Massage gently into skin
  • Follow with an appropriate care product such as Eucerin DermoPurifyer Mattifying Fluid
  • Avoid contact with your eyes

Tip: Try out on a small area of skin first. A slight tingling sensation may occur but, if your skin show a visible reaction, consult your dermatologist or pharmacist.

This product contains Alpha Hydroxy Acids that may increase your skin’s sensitivity to the sun and the possibility of sunburn. As a result, we recommend you limit your exposure to the sun while using this product and for a week after. During that period, and after, be sure to apply sun protection in the morning. Try Eucerin Oil Control Sun Gel-Cream Dry Touch SPF 50+.

Your daily routine

The care product you use depends on the severity of your acne and on the type of treatment you are undergoing. 

If you are using medical treatment for acne, Eucerin DermoPurifyer Adjunctive Cream helps to alleviate some of the symptoms such as intense dryness. It should be applied five minutes after your medication so the treatment can absorb fully. 

If you have mild to moderate acne, but are not undergoing medical acne treatment, use a soothing and mattifying moisturiser such as Eucerin DermoPurifyer Mattifying Fluid in the morning and evening.

For clearer and smoother-looking skin over time, you may also like to incorporate our skin renewal treatment into your routine. It is suitable for all blemish-prone skin that is not undergoing medical acne treatment and should be used once a day only − ideally in the evening. You can use it before the mattifying fluid or on its own.

Cleanse skin in the morning and evening:

  • am: to remove the sebum and dead skin cells that have accumulated overnight
  • pm: to remove make-up and free skin from the day’s dirt

Use gentle cleansing products such as Eucerin DermoPurifyer Cleansing Gel with lukewarm water and follow with an appropriate toner. You may also benefit from using a scrub once a week to unclog pores and refine skin texture.

We do not recommend using an alcohol-based toner and the scrub alongside acne medication as Isotretinoin, Benzoyl Peroxide and Antibiotics can make skin more sensitive. If you like the refreshing feel of a toner, try the alcohol-free Eucerin DermoPurifyer Micellar Water instead.

Cover blemishes and even out skin tone with foundation and/or a concealer. Choose products that are non-comedogenic (i.e. that will not block pores) and, ideally, ones that contain ingredients that work to improve the condition of blemish-prone skin. Be sure to remove all make-up before you go to bed.

Sun protection is an important step in your morning routine. Blemishes can cause pigmentation issues if over-exposed to the sun, and acne medications can make blemish-prone skin even more sensitive to UV rays. Eucerin Oil Control Sun Gel-Cream Dry Touch SPF 50+ offers the levels of protection that your skin needs and should be applied before your cover-up and make-up. If you’re applying sun protection after a topical acne treatment wait five minutes to allow the treatment to fully absorb.  

Do's and Don'ts

Don't use this product if...

Use this product for...

Eucerin DermoPurifyer Skin Renewal Treatment starts working from day one and results are visible after just one week.

Eucerin DermoPURIFYER Skin care for impure skin

Eucerin DermoPURIFYER is a range of effective dermo cosmetic solutions for impure skin. Its ingredient combination addresses the four key factors of impure skin: hyperkeratosis (disrupted skin cell shedding), seborrhea (increased sebum production), microbial colonisation (increased bacteria proliferation) and redness of the skin. Eucerin DermoPURIFYER products have been proven in clinical and dermatological studies to be both effective and very good for skin tolerability.

Overall rating
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Combining products

I have been actively using the skin renewal treatment for a couple of months,however have just read on your site that it is advised to follow with the mattifying fluid which I use during the day. Is this necessary? And if so, may I enquire as to why this is? I like understanding how my skincare works and this product has been just okay for me... Wondering if following with the mattifying fluid would have a better result somehow...
Eucerin ZA

Hi Kiara. 

Thank you for your Review.  It is indeed advisable to use the Mattifying Fluid which is the moisturising day cream in this product range.  It is important to keep your skin well-nourished and hydrated and this product will ensure that this is the case.  The Mattifying Fluid can be used during the day and at night.  If you are not currently using the Cleansing Gel in the DermoPurifyer range, we would recommend that you perhaps consider doing so.  We really appreciate your loyalty to the Eucerin brand and thank you again for getting in touch.

Many Thanks,

Eucerin ZA Team


Large Pores

I'm interested in purchasing this product my areas of concern are large pores & smooth texture, can it help with the mentioned skin concerns?
Eucerin ZA

Thank you for your Review.  Please could you send us your e-mail address and cellphone number to: so that we can get in touch to discuss your particular needs. 

Many thanks,

Eucerin ZA Team


eucerin skin renewal

I am using whole range of the dermopurifyer for both pimples and pigmentation marks. Pimples have stopped for the past fortnight but the dark marks are still evident. Should I switch on to the even brighter range or I should just continue on dermopurifyer?
Eucerin ZA

Hi Lally. 

The DermoPurifyer range will not actively remove pimple scarring or dark marks.  This range is formulated to address the issues surrounding problem skin and will also assist with the reduction in the formation of pimples on the skin.  This would be the reason you have experienced an improvement in your skin condition.  Please always remember never to pick or squeeze your pimples, as this will indeed cause scarring on the skin.  

Many Thanks,

Eucerin ZA Team


Dermopurifyer Skin Renewal - Thumbs Down

I've always been a Eucerin fan like FOREVER!!! The whole Dermopurifyer ranger of cleanser and scrub helped me a lot cause i stopped having pimples and used the Even Brighter range Day Cream for pigmentation however when the Dermopurifyer introduced its new product of Skin Renewal Treatment it really caused a MAJOR SKIN BREAKOUT. I am totally not happy with this product and it made my skin worse within two weeks of usage. So I have discontinued it and i feel like i wasted money. Is it possible to return it back to the shop as I am not happy with the results. So i can switch it for another Eucerin product for evening use? I am based in South Africa and what channels can I take to go about this?
Eucerin ZA


Thank you for your review.  We are sorry to hear that the DermoPurifyer Skin Renewal Treatment is not agreeing with your skin.  We will gladly re-test the control batch of product that you have purchased.  Please could you send a blank e-mail to: so that we can correspond with you directly to obtain specific information.   

Many thanks,

Eucerin ZA Team


Combination skin (oily T-Zone)

Im interested in your products and would like you to recommend a 3 step regimen. I have dark marks due to break outs from time to time. Uneven skin tone due to chin area being dry. Also treatment of fine lines im 33 years
Eucerin ZA

Hi Kido123,

Please could you send an e-mail, advising us of your telephone number, to, following which a consultant will get in touch with you to discuss your specific requirements. 

Many thanks,

Eucerin ZA Team