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  • 1/6 Eucerin DermoPurifyer Adjunctive Soothing Cream
  • 2/6 Eucerin DermoPurifyer Adjunctive Cream benefits
  • 3/6 woman applying Eucerin DermoPurifyer Adjunctive Cream to face
  • 4/6 Eucerin DermoPurifyer Adjunctive Cream ingredients
  • 5/6 Eucerin DermoPurifyer Adjunctive Cream testimonial
  • 6/6 Eucerin DermoPurifyer Adjunctive Cream recommendation

DermoPurifyer Adjunctive Soothing Cream 50 ml

Soothes skin under medical acne treatment
Intensively moisturises and reduces dryness
Calms skin irritation and redness

Soothes and intensely moisturises skin undergoing medical acne treatment

A moisturiser for acne prone skin that alleviates the side effects of acne medication. It’s intensively hydrating, non-sticky formula soothes irritations, reduces tightness and helps you to regain control over demanding blemish-prone skin.

Product info

Moisturiser for acne-prone skin

Eucerin DermoPurifyer Adjunctive Soothing Cream is a moisturiser for acne-prone skin specially formulated for people undergoing medical acne treatment.

One of the side effects of acne medication is that it frequently causes severe dryness in skin. This intensely moisturising, non-greasy cream soothes these symptoms. Ceramides support skin’s protective barrier and reduce moisture loss, SymSitive* helps to calm irritation such as stinging and burning directly at source and Licochalcone A helps to reduce redness. The formula helps to bring demanding, blemish and acne-prone skin under control and it feels smooth and supple after the first application.

Eucerin DermoPurifyer Adjunctive Cream is suitable for use during pregnancy.

* Registered trademark of Symrise AG, Germany

Clinical and dermatological studies

Clinical and dermatological studies prove good skin tolerability and efficacy on blemish-prone skin. Suitable for sensitive skin.

In a self-assessment study a sample of 58 men and women aged between 16 and 43 (average age 24) applied Eucerin DermoPurifyer Adjunctive Cream twice a day for two weeks. At the time of the study, all respondents had been undergoing medical acne treatment for at least two weeks.

The patients reported the following results:

  • 96%: skin feels comfortable after regular application
  • 94%: silky smooth texture
  • 93%: reduces feelings of tightness
  • 91%: soothes skin under medical acne treatment
  • 91%: spreads easily
  • 91%: skin feels softer after the first application
  • 90%: alleviates side-effects of acne treatment
  • 89%: the cream reduces stinging and burning


Texture of DermoPurifyer adjunctive soothing cream

  • non-comedogenic
  • non greasy
  • fragrance free

How To Use



  • Use daily in the morning and/or in the evening – as often as necessary
  • Apply a chickpea-sized amount to a thoroughly cleansed face (try Eucerin DermoPurifyer Cleansing Gel)
  • Massage gently
  • Avoid contact with your eyes
  • Follow with an appropriate sun protection product such as Eucerin Oil Control Sun Gel-Cream Dry Touch SPF 50+. This is important to help prevent pigmentation issues in blemish-prone skin
  • Eucerin DermoPurifyer Adjunctive Cream is an excellent base for make-up


Your daily skincare routines

Cleanse and tone

Cleanse skin in the morning and evening:

  • am: to remove the sebum and dead skin cells that have accumulated overnight
  • pm: to remove make-up and free skin from the day’s dirt

Use gentle cleansing products such as Eucerin DermoPurifyer Cleansing Gel with lukewarm water and follow with an appropriate toner. You may also benefit from using a scrub once a week to unclog pores and refine skin texture.

We do not recommend using an alcohol-based toner and the scrub alongside acne medication as it can make skin more sensitive.

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The care product you use depends on the severity of your acne and on the type of treatment you are undergoing.


If you are using medical treatment for acne, Eucerin DermoPurifyer Adjunctive Cream helps to alleviate some of the symptoms such as intense dryness. It should be applied five minutes after your medication so the treatment can absorb fully.


If you have mild to moderate acne, but are not undergoing medical acne treatment, use a soothing and mattifying moisturiser such as Eucerin DermoPurifyer Mattifying Fluid in the morning and evening.


For clearer and smoother-looking skin over time, you may also like to incorporate our skin renewal treatment into your routine. It is suitable for all blemish-prone skin that is not undergoing medical acne treatment and should be used once a day only − ideally in the evening. You can use it before the mattifying fluid or on its own.

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Sun Protection

Sun protection is an important step in your morning routine. Blemishes can cause pigmentation issues if over-exposed to the sun, and acne medications can make blemish-prone skin even more sensitive to UV rays. Eucerin Oil Control Sun Gel-Cream Dry Touch SPF 50+ offers the levels of protection that your skin needs and should be applied before your cover-up and make-up. If you’re applying sun protection after a topical acne treatment wait five minutes to allow the treatment to fully absorb.

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Concealer and make-up

Cover blemishes and even out skin tone with foundation and/or a concealer. Choose products that are non-comedogenic (i.e. that will not block pores) and, ideally, ones that contain ingredients that work to improve the condition of blemish-prone skin. Be sure to remove all make-up before you go to bed.

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Is this the right product for my skin?

Use this product if …

- Your skin has been dried out and irritated by medical acne treatment.

Try a different product if …

- You are no longer having medical treatment for your acne: Try Eucerin DermoPurifyer Mattifying Fluid.


FAQ (6)

from 24 reviews
  • Ash 2023/09/20
    Love this !
    Best moisturiser ever especially while on Orotane for acne. Any suggestions for a make up/ foundation that works well together with this and the spf 50 sun gel? The one I am currently using (catrice) cakes if I use the eucerin products mentioned above.


    Hi Ash.  Thank you for your enquiry.  Unfortunately we do not trade in the make-up market at all.  May we suggest that you discuss this directly with the manufacturer of the item that you currently use.  When applying the Adjunctive Soothing Care Cream, remember to "pat" it into the skin, rather than rubbing as this can help to alleviate the problem of pilling when using a foundation.  

  • KC 2023/06/16
    Dry Acne prone skin
    I’ve been using this for a few days now. My Dr recommended. But it’s been making my skin really dry. What alternative can ???. I also have acne prone skin


    Hi KC.  The Dermo Purifyer Adjunctive Soothing Cream.  We are making the assumption that you are currently taking acne medication as this product is formulated to address the dryness associated with the side-effects of the acne medication (i.e. dryness).  The Adjunctive Soothing Cream ensures sufficient moisture to avoid the dryness.  It is very unusual to experience dryness from using this particular product.  Perhaps it is the acne medication that is drying out the skin.  Having said that, we would always recommend that if you are under the guidance of a Dermatologist, that you provide feedback about the product that has been recommended for you so that a decision can be made as to an alternative which may better suit your particular skin condition.  

  • Uniii 2023/03/28
    My doctor recommended these acne range products but I don't know which moisturizer to use with epiduo
    Can I use this product with epiduo

    Hi Uniii.

    The Adjunctive Soothing Cream should be used where dryness of the skin has occurred when taking acne medication. If your skin is still normal whilst using the Epiduo Gel, we would recommend using the Mattifying Fluid to moisturise in the morning and at night. For more information on this product, please click on the following link to our web-site: https://www.eucerin.co.za/products/dermo-purifyer/mattifying-fluid.

    Many thanks,

    Eucerin ZA

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Our brand values

Pioneers in skincare

We deliver a holistic dermo-cosmetic approach to protect your skin, keep it healthy and radiant.

Recommended by dermatologists

We work together with leading dermatologist and pharmacist partners around the world to create innovative and effective skincare products they can trust and recommend.

Committed to innovation

For over 100 years, we have dedicated ourselves to researching and innovating in the field of skin science. We believe in creating active ingredients and soothing formulas with high tolerability that work to help you live your life better each day.